Serologic Follow-up of Middle East Respiratory Syndrome Coronavirus Cases and Contacts—Abu Dhabi, United Arab Emirates
Identifieur interne : 000806 ( Main/Exploration ); précédent : 000805; suivant : 000807Serologic Follow-up of Middle East Respiratory Syndrome Coronavirus Cases and Contacts—Abu Dhabi, United Arab Emirates
Auteurs : Farida Ismail Al Hosani [Émirats arabes unis] ; Lindsay Kim [Géorgie (pays), États-Unis] ; Ahmed Khudhair [Émirats arabes unis] ; Huong Pham [Géorgie (pays)] ; Mariam Al Mulla [Émirats arabes unis] ; Zyad Al Bandar [Émirats arabes unis] ; Krishna Pradeep [Émirats arabes unis] ; Kheir Abou Elkheir [Émirats arabes unis] ; Stefan Weber [Émirats arabes unis] ; Mary Khoury [Émirats arabes unis] ; George Donnelly [Émirats arabes unis] ; Naima Younis [Émirats arabes unis] ; Feda El Saleh [Émirats arabes unis] ; Muna Abdalla [Émirats arabes unis] ; Hala Imambaccus [Émirats arabes unis] ; Lia M. Haynes [Géorgie (pays)] ; Natalie J. Thornburg [Géorgie (pays)] ; Jennifer L. Harcourt [Géorgie (pays)] ; Congrong Miao [Géorgie (pays)] ; Azaibi Tamin [Géorgie (pays)] ; Aron J. Hall [Géorgie (pays)] ; Elizabeth S. Russell [Géorgie (pays)] ; Aaron M. Harris [États-Unis, Géorgie (pays)] ; Craig Kiebler [Géorgie (pays)] ; Roger A. Mir [Géorgie (pays)] ; Kimberly Pringle [Géorgie (pays)] ; Negar N. Alami [Géorgie (pays)] ; Glen R. Abedi [Géorgie (pays)] ; Susan I. Gerber [Géorgie (pays)]Source :
- Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America [ 1058-4838 ] ; 2018.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Anticorps antiviraux (sang), Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie), Enfant, Enfant d'âge préscolaire, Facteurs de risque, Femelle, Humains, Infections à coronavirus (immunologie), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Jeune adulte, Mâle, Nourrisson, Nouveau-né, Santé de la famille, Sujet âgé, Sujet âgé de 80 ans ou plus, Technique d'immunofluorescence indirecte, Test ELISA, Transmission de maladie infectieuse, Émirats arabes unis (épidémiologie), Études séroépidémiologiques.
- MESH :
- immunologie : Coronavirus du syndrome respiratoire du Moyen-Orient, Infections à coronavirus.
- sang : Anticorps antiviraux.
- épidémiologie : Infections à coronavirus, Émirats arabes unis.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Facteurs de risque, Femelle, Humains, Jeune adulte, Mâle, Nourrisson, Nouveau-né, Santé de la famille, Sujet âgé, Sujet âgé de 80 ans ou plus, Technique d'immunofluorescence indirecte, Test ELISA, Transmission de maladie infectieuse, Études séroépidémiologiques.
- Wicri :
- geographic : Émirats arabes unis.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Antibodies, Viral (blood), Child, Child, Preschool, Coronavirus Infections (epidemiology), Coronavirus Infections (immunology), Coronavirus Infections (transmission), Disease Transmission, Infectious, Enzyme-Linked Immunosorbent Assay, Family Health, Female, Fluorescent Antibody Technique, Indirect, Humans, Infant, Infant, Newborn, Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus (immunology), Risk Factors, Seroepidemiologic Studies, United Arab Emirates (epidemiology), Young Adult.
- MESH :
- chemical , blood : Antibodies, Viral.
- geographic , epidemiology : United Arab Emirates.
- epidemiology : Coronavirus Infections.
- immunology : Coronavirus Infections, Middle East Respiratory Syndrome Coronavirus.
- transmission : Coronavirus Infections.
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Disease Transmission, Infectious, Enzyme-Linked Immunosorbent Assay, Family Health, Female, Fluorescent Antibody Technique, Indirect, Humans, Infant, Infant, Newborn, Male, Middle Aged, Risk Factors, Seroepidemiologic Studies, Young Adult.
Abstract
Although there is evidence of person-to-person transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in household and healthcare settings, more data are needed to describe and better understand the risk factors and transmission routes in both settings, as well as the extent to which disease severity affects transmission.
A seroepidemiological investigation was conducted among MERS-CoV case patients (cases) and their household contacts to investigate transmission risk in Abu Dhabi, United Arab Emirates. Cases diagnosed between 1 January 2013 and 9 May 2014 and their household contacts were approached for enrollment. Demographic, clinical, and exposure history data were collected. Sera were screened by MERS-CoV nucleocapsid protein enzyme-linked immunosorbent assay and indirect immunofluorescence, with results confirmed by microneutralization assay.
Thirty-one of 34 (91%) case patients were asymptomatic or mildly symptomatic and did not require oxygen during hospitalization. MERS-CoV antibodies were detected in 13 of 24 (54%) case patients with available sera, including 1 severely symptomatic, 9 mildly symptomatic, and 3 asymptomatic case patients. No serologic evidence of MERS-CoV transmission was found among 105 household contacts with available sera.
Transmission of MERS-CoV was not documented in this investigation of mostly asymptomatic and mildly symptomatic cases and their household contacts. These results have implications for clinical management of cases and formulation of isolation policies to reduce the risk of transmission.
Url:
DOI: 10.1093/cid/ciy503
PubMed: 29905769
PubMed Central: 7108211
Affiliations:
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Le document en format XML
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Abedi</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">29905769</idno><idno type="pmc">7108211</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108211</idno><idno type="RBID">PMC:7108211</idno><idno type="doi">10.1093/cid/ciy503</idno><date when="2018">2018</date><idno type="wicri:Area/Pmc/Corpus">000B81</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000B81</idno><idno type="wicri:Area/Pmc/Curation">000B81</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000B81</idno><idno 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(pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="AF0003">United States Public Health Service, Rockville, Maryland</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>United States Public Health Service, Rockville</wicri:cityArea></affiliation></author><author><name sortKey="Khudhair, Ahmed" sort="Khudhair, Ahmed" uniqKey="Khudhair A" first="Ahmed" last="Khudhair">Ahmed Khudhair</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Health–Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Department of Health–Abu Dhabi</wicri:regionArea></affiliation></author><author><name sortKey="Pham, Huong" sort="Pham, Huong" uniqKey="Pham H" first="Huong" last="Pham">Huong Pham</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Al Mulla, Mariam" sort="Al Mulla, Mariam" uniqKey="Al Mulla M" first="Mariam" last="Al Mulla">Mariam Al Mulla</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Health–Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Department of Health–Abu Dhabi</wicri:regionArea></affiliation></author><author><name sortKey="Al Bandar, Zyad" sort="Al Bandar, Zyad" uniqKey="Al Bandar Z" first="Zyad" last="Al Bandar">Zyad Al Bandar</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Health–Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Department of Health–Abu Dhabi</wicri:regionArea></affiliation></author><author><name sortKey="Pradeep, Krishna" sort="Pradeep, Krishna" uniqKey="Pradeep K" first="Krishna" last="Pradeep">Krishna Pradeep</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Health–Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Department of Health–Abu Dhabi</wicri:regionArea></affiliation></author><author><name sortKey="Elkheir, Kheir Abou" sort="Elkheir, Kheir Abou" uniqKey="Elkheir K" first="Kheir Abou" last="Elkheir">Kheir Abou Elkheir</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Health–Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Department of Health–Abu Dhabi</wicri:regionArea></affiliation></author><author><name sortKey="Weber, Stefan" sort="Weber, Stefan" uniqKey="Weber S" first="Stefan" last="Weber">Stefan Weber</name><affiliation wicri:level="1"><nlm:aff id="AF0004">Sheikh Khalifa Medical Laboratory, Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Sheikh Khalifa Medical Laboratory, Abu Dhabi</wicri:regionArea><wicri:noRegion>Abu Dhabi</wicri:noRegion></affiliation></author><author><name sortKey="Khoury, Mary" sort="Khoury, Mary" uniqKey="Khoury M" first="Mary" last="Khoury">Mary Khoury</name><affiliation wicri:level="1"><nlm:aff id="AF0004">Sheikh Khalifa Medical Laboratory, Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Sheikh Khalifa Medical Laboratory, Abu Dhabi</wicri:regionArea><wicri:noRegion>Abu Dhabi</wicri:noRegion></affiliation></author><author><name sortKey="Donnelly, George" sort="Donnelly, George" uniqKey="Donnelly G" first="George" last="Donnelly">George Donnelly</name><affiliation wicri:level="1"><nlm:aff id="AF0004">Sheikh Khalifa Medical Laboratory, Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Sheikh Khalifa Medical Laboratory, Abu Dhabi</wicri:regionArea><wicri:noRegion>Abu Dhabi</wicri:noRegion></affiliation></author><author><name sortKey="Younis, Naima" sort="Younis, Naima" uniqKey="Younis N" first="Naima" last="Younis">Naima Younis</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Health–Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Department of Health–Abu Dhabi</wicri:regionArea></affiliation></author><author><name sortKey="El Saleh, Feda" sort="El Saleh, Feda" uniqKey="El Saleh F" first="Feda" last="El Saleh">Feda El Saleh</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Health–Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Department of Health–Abu Dhabi</wicri:regionArea></affiliation></author><author><name sortKey="Abdalla, Muna" sort="Abdalla, Muna" uniqKey="Abdalla M" first="Muna" last="Abdalla">Muna Abdalla</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Health–Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Department of Health–Abu Dhabi</wicri:regionArea></affiliation></author><author><name sortKey="Imambaccus, Hala" sort="Imambaccus, Hala" uniqKey="Imambaccus H" first="Hala" last="Imambaccus">Hala Imambaccus</name><affiliation wicri:level="1"><nlm:aff id="AF0004">Sheikh Khalifa Medical Laboratory, Abu Dhabi, United Arab Emirates</nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea>Sheikh Khalifa Medical Laboratory, Abu Dhabi</wicri:regionArea><wicri:noRegion>Abu Dhabi</wicri:noRegion></affiliation></author><author><name sortKey="Haynes, Lia M" sort="Haynes, Lia M" uniqKey="Haynes L" first="Lia M" last="Haynes">Lia M. Haynes</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Thornburg, Natalie J" sort="Thornburg, Natalie J" uniqKey="Thornburg N" first="Natalie J" last="Thornburg">Natalie J. Thornburg</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Harcourt, Jennifer L" sort="Harcourt, Jennifer L" uniqKey="Harcourt J" first="Jennifer L" last="Harcourt">Jennifer L. Harcourt</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Miao, Congrong" sort="Miao, Congrong" uniqKey="Miao C" first="Congrong" last="Miao">Congrong Miao</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Tamin, Azaibi" sort="Tamin, Azaibi" uniqKey="Tamin A" first="Azaibi" last="Tamin">Azaibi Tamin</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Hall, Aron J" sort="Hall, Aron J" uniqKey="Hall A" first="Aron J" last="Hall">Aron J. Hall</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Russell, Elizabeth S" sort="Russell, Elizabeth S" uniqKey="Russell E" first="Elizabeth S" last="Russell">Elizabeth S. Russell</name><affiliation wicri:level="1"><nlm:aff id="AF0005">Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Harris, Aaron M" sort="Harris, Aaron M" uniqKey="Harris A" first="Aaron M" last="Harris">Aaron M. Harris</name><affiliation wicri:level="2"><nlm:aff id="AF0003">United States Public Health Service, Rockville, Maryland</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>United States Public Health Service, Rockville</wicri:cityArea></affiliation><affiliation wicri:level="1"><nlm:aff id="AF0005">Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Kiebler, Craig" sort="Kiebler, Craig" uniqKey="Kiebler C" first="Craig" last="Kiebler">Craig Kiebler</name><affiliation wicri:level="1"><nlm:aff id="AF0005">Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Mir, Roger A" sort="Mir, Roger A" uniqKey="Mir R" first="Roger A" last="Mir">Roger A. Mir</name><affiliation wicri:level="1"><nlm:aff id="AF0006">Division of Health Informatics and Surveillance, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Health Informatics and Surveillance, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Pringle, Kimberly" sort="Pringle, Kimberly" uniqKey="Pringle K" first="Kimberly" last="Pringle">Kimberly Pringle</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="AF0005">Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Alami, Negar N" sort="Alami, Negar N" uniqKey="Alami N" first="Negar N" last="Alami">Negar N. Alami</name><affiliation wicri:level="1"><nlm:aff id="AF0005">Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Abedi, Glen R" sort="Abedi, Glen R" uniqKey="Abedi G" first="Glen R" last="Abedi">Glen R. Abedi</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia</nlm:aff><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author></analytic><series><title level="j">Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America</title><idno type="ISSN">1058-4838</idno><idno type="eISSN">1537-6591</idno><imprint><date when="2018">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Antibodies, Viral (blood)</term><term>Child</term><term>Child, Preschool</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (immunology)</term><term>Coronavirus Infections (transmission)</term><term>Disease Transmission, Infectious</term><term>Enzyme-Linked Immunosorbent Assay</term><term>Family Health</term><term>Female</term><term>Fluorescent Antibody Technique, Indirect</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Male</term><term>Middle Aged</term><term>Middle East Respiratory Syndrome Coronavirus (immunology)</term><term>Risk Factors</term><term>Seroepidemiologic Studies</term><term>United Arab Emirates (epidemiology)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Anticorps antiviraux (sang)</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Infections à coronavirus (immunologie)</term><term>Infections à coronavirus (transmission)</term><term>Infections à coronavirus (épidémiologie)</term><term>Jeune adulte</term><term>Mâle</term><term>Nourrisson</term><term>Nouveau-né</term><term>Santé de la famille</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Technique d'immunofluorescence indirecte</term><term>Test ELISA</term><term>Transmission de maladie infectieuse</term><term>Émirats arabes unis (épidémiologie)</term><term>Études séroépidémiologiques</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>United Arab Emirates</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Coronavirus Infections</term><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antiviraux</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Émirats arabes unis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Child</term><term>Child, Preschool</term><term>Disease Transmission, Infectious</term><term>Enzyme-Linked Immunosorbent Assay</term><term>Family Health</term><term>Female</term><term>Fluorescent Antibody Technique, Indirect</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Male</term><term>Middle Aged</term><term>Risk Factors</term><term>Seroepidemiologic Studies</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Nourrisson</term><term>Nouveau-né</term><term>Santé de la famille</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Technique d'immunofluorescence indirecte</term><term>Test ELISA</term><term>Transmission de maladie infectieuse</term><term>Études séroépidémiologiques</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Émirats arabes unis</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><sec id="s1"><title>Background</title><p>Although there is evidence of person-to-person transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in household and healthcare settings, more data are needed to describe and better understand the risk factors and transmission routes in both settings, as well as the extent to which disease severity affects transmission.</p></sec><sec id="s2"><title>Methods</title><p>A seroepidemiological investigation was conducted among MERS-CoV case patients (cases) and their household contacts to investigate transmission risk in Abu Dhabi, United Arab Emirates. Cases diagnosed between 1 January 2013 and 9 May 2014 and their household contacts were approached for enrollment. Demographic, clinical, and exposure history data were collected. Sera were screened by MERS-CoV nucleocapsid protein enzyme-linked immunosorbent assay and indirect immunofluorescence, with results confirmed by microneutralization assay.</p></sec><sec id="s3"><title>Results</title><p>Thirty-one of 34 (91%) case patients were asymptomatic or mildly symptomatic and did not require oxygen during hospitalization. MERS-CoV antibodies were detected in 13 of 24 (54%) case patients with available sera, including 1 severely symptomatic, 9 mildly symptomatic, and 3 asymptomatic case patients. No serologic evidence of MERS-CoV transmission was found among 105 household contacts with available sera.</p></sec><sec id="s4"><title>Conclusions</title><p>Transmission of MERS-CoV was not documented in this investigation of mostly asymptomatic and mildly symptomatic cases and their household contacts. These results have implications for clinical management of cases and formulation of isolation policies to reduce the risk of transmission.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Ben Embarek, Pk" uniqKey="Ben Embarek P">PK Ben Embarek</name></author><author><name sortKey="Van Kerkhove, Md" uniqKey="Van Kerkhove M">MD Van Kerkhove</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Alraddadi, Bm" uniqKey="Alraddadi B">BM Alraddadi</name></author><author><name sortKey="Watson, Jt" uniqKey="Watson J">JT Watson</name></author><author><name sortKey="Almarashi, A" uniqKey="Almarashi A">A Almarashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Hosani, Fi" uniqKey="Al Hosani F">FI Al Hosani</name></author><author><name sortKey="Pringle, K" uniqKey="Pringle K">K Pringle</name></author><author><name sortKey="Al Mulla, M" uniqKey="Al Mulla M">M Al Mulla</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alshukairi, An" uniqKey="Alshukairi A">AN Alshukairi</name></author><author><name sortKey="Khalid, I" uniqKey="Khalid I">I Khalid</name></author><author><name sortKey="Ahmed, Wa" uniqKey="Ahmed W">WA Ahmed</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Choe, Pg" uniqKey="Choe P">PG Choe</name></author><author><name sortKey="Perera, R" uniqKey="Perera R">R Perera</name></author><author><name sortKey="Park, Wb" uniqKey="Park W">WB Park</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Payne, Dc" uniqKey="Payne D">DC Payne</name></author><author><name sortKey="Iblan, I" uniqKey="Iblan I">I Iblan</name></author><author><name sortKey="Rha, B" uniqKey="Rha B">B Rha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Min, Ck" uniqKey="Min C">CK Min</name></author><author><name sortKey="Cheon, S" uniqKey="Cheon S">S Cheon</name></author><author><name sortKey="Ha, Ny" uniqKey="Ha N">NY Ha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oboho, Ik" uniqKey="Oboho I">IK Oboho</name></author><author><name sortKey="Tomczyk, Sm" uniqKey="Tomczyk S">SM Tomczyk</name></author><author><name sortKey="Al Asmari, Am" uniqKey="Al Asmari A">AM Al-Asmari</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B Meyer</name></author><author><name sortKey="Muller, Ma" uniqKey="Muller M">MA Müller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Assiri, A" uniqKey="Assiri A">A Assiri</name></author><author><name sortKey="Mcgeer, A" uniqKey="Mcgeer A">A McGeer</name></author><author><name sortKey="Perl, Tm" uniqKey="Perl T">TM Perl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name></author><author><name sortKey="Zumla, Ai" uniqKey="Zumla A">AI Zumla</name></author><author><name sortKey="Al Hakeem, Rf" uniqKey="Al Hakeem R">RF Al-Hakeem</name></author><author><name sortKey="Al Rabeeah, Aa" uniqKey="Al Rabeeah A">AA Al-Rabeeah</name></author><author><name sortKey="Stephens, Gm" uniqKey="Stephens G">GM Stephens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arwady, Ma" uniqKey="Arwady M">MA Arwady</name></author><author><name sortKey="Alraddadi, B" uniqKey="Alraddadi B">B Alraddadi</name></author><author><name sortKey="Basler, C" uniqKey="Basler C">C Basler</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Al Abdallat, Mm" uniqKey="Al Abdallat M">MM Al-Abdallat</name></author><author><name sortKey="Payne, Dc" uniqKey="Payne D">DC Payne</name></author><author><name sortKey="Alqasrawi, S" uniqKey="Alqasrawi S">S Alqasrawi</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Hunter, Jc" uniqKey="Hunter J">JC Hunter</name></author><author><name sortKey="Nguyen, D" uniqKey="Nguyen D">D Nguyen</name></author><author><name sortKey="Aden, B" uniqKey="Aden B">B Aden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alraddadi, Bm" uniqKey="Alraddadi B">BM Alraddadi</name></author><author><name sortKey="Al Salmi, Hs" uniqKey="Al Salmi H">HS Al-Salmi</name></author><author><name sortKey="Jacobs Slifka, K" uniqKey="Jacobs Slifka K">K Jacobs-Slifka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arabi, Ym" uniqKey="Arabi Y">YM Arabi</name></author><author><name sortKey="Arifi, Aa" uniqKey="Arifi A">AA Arifi</name></author><author><name sortKey="Balkhy, Hh" uniqKey="Balkhy H">HH Balkhy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saad, M" uniqKey="Saad M">M Saad</name></author><author><name sortKey="Omrani, As" uniqKey="Omrani A">AS Omrani</name></author><author><name sortKey="Baig, K" uniqKey="Baig K">K Baig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arabi, Ym" uniqKey="Arabi Y">YM Arabi</name></author><author><name sortKey="Balkhy, Hh" uniqKey="Balkhy H">HH Balkhy</name></author><author><name sortKey="Hayden, Fg" uniqKey="Hayden F">FG Hayden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Sw" uniqKey="Kim S">SW Kim</name></author><author><name sortKey="Park, Jw" uniqKey="Park J">JW Park</name></author><author><name sortKey="Jung, Hd" uniqKey="Jung H">HD Jung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ko, Jh" uniqKey="Ko J">JH Ko</name></author><author><name sortKey="Muller, Ma" uniqKey="Muller M">MA Müller</name></author><author><name sortKey="Seok, H" uniqKey="Seok H">H Seok</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corman, Vm" uniqKey="Corman V">VM Corman</name></author><author><name sortKey="Albarrak, Am" uniqKey="Albarrak A">AM Albarrak</name></author><author><name sortKey="Omrani, As" uniqKey="Omrani A">AS Omrani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, Wb" uniqKey="Park W">WB Park</name></author><author><name sortKey="Perera, Ra" uniqKey="Perera R">RA Perera</name></author><author><name sortKey="Choe, Pg" uniqKey="Choe P">PG Choe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Gethamy, M" uniqKey="Al Gethamy M">M Al-Gethamy</name></author><author><name sortKey="Corman, Vm" uniqKey="Corman V">VM Corman</name></author><author><name sortKey="Hussain, R" uniqKey="Hussain R">R Hussain</name></author><author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name></author><author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hall, Aj" uniqKey="Hall A">AJ Hall</name></author><author><name sortKey="Tokars, Ji" uniqKey="Tokars J">JI Tokars</name></author><author><name sortKey="Badreddine, Sa" uniqKey="Badreddine S">SA Badreddine</name></author></analytic></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Géorgie (pays)</li><li>Émirats arabes unis</li><li>États-Unis</li></country><region><li>Maryland</li></region></list><tree><country name="Émirats arabes unis"><noRegion><name sortKey="Al Hosani, Farida Ismail" sort="Al Hosani, Farida Ismail" uniqKey="Al Hosani F" first="Farida Ismail" last="Al Hosani">Farida Ismail Al Hosani</name></noRegion><name sortKey="Abdalla, Muna" sort="Abdalla, Muna" uniqKey="Abdalla M" first="Muna" last="Abdalla">Muna Abdalla</name><name sortKey="Al Bandar, Zyad" sort="Al Bandar, Zyad" uniqKey="Al Bandar Z" first="Zyad" last="Al Bandar">Zyad Al Bandar</name><name sortKey="Al Mulla, Mariam" sort="Al Mulla, Mariam" uniqKey="Al Mulla M" first="Mariam" last="Al Mulla">Mariam Al Mulla</name><name sortKey="Donnelly, George" sort="Donnelly, George" uniqKey="Donnelly G" first="George" last="Donnelly">George Donnelly</name><name sortKey="El Saleh, Feda" sort="El Saleh, Feda" uniqKey="El Saleh F" first="Feda" last="El Saleh">Feda El Saleh</name><name sortKey="Elkheir, Kheir Abou" sort="Elkheir, Kheir Abou" uniqKey="Elkheir K" first="Kheir Abou" last="Elkheir">Kheir Abou Elkheir</name><name sortKey="Imambaccus, Hala" sort="Imambaccus, Hala" uniqKey="Imambaccus H" first="Hala" last="Imambaccus">Hala Imambaccus</name><name sortKey="Khoury, Mary" sort="Khoury, Mary" uniqKey="Khoury M" first="Mary" last="Khoury">Mary Khoury</name><name sortKey="Khudhair, Ahmed" sort="Khudhair, Ahmed" uniqKey="Khudhair A" first="Ahmed" last="Khudhair">Ahmed Khudhair</name><name sortKey="Pradeep, Krishna" sort="Pradeep, Krishna" uniqKey="Pradeep K" first="Krishna" last="Pradeep">Krishna Pradeep</name><name sortKey="Weber, Stefan" sort="Weber, Stefan" uniqKey="Weber S" first="Stefan" last="Weber">Stefan Weber</name><name sortKey="Younis, Naima" sort="Younis, Naima" uniqKey="Younis N" first="Naima" last="Younis">Naima Younis</name></country><country name="Géorgie (pays)"><noRegion><name sortKey="Kim, Lindsay" sort="Kim, Lindsay" uniqKey="Kim L" first="Lindsay" last="Kim">Lindsay Kim</name></noRegion><name sortKey="Abedi, Glen R" sort="Abedi, Glen R" uniqKey="Abedi G" first="Glen R" last="Abedi">Glen R. Abedi</name><name sortKey="Alami, Negar N" sort="Alami, Negar N" uniqKey="Alami N" first="Negar N" last="Alami">Negar N. Alami</name><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name><name sortKey="Hall, Aron J" sort="Hall, Aron J" uniqKey="Hall A" first="Aron J" last="Hall">Aron J. Hall</name><name sortKey="Harcourt, Jennifer L" sort="Harcourt, Jennifer L" uniqKey="Harcourt J" first="Jennifer L" last="Harcourt">Jennifer L. Harcourt</name><name sortKey="Harris, Aaron M" sort="Harris, Aaron M" uniqKey="Harris A" first="Aaron M" last="Harris">Aaron M. Harris</name><name sortKey="Haynes, Lia M" sort="Haynes, Lia M" uniqKey="Haynes L" first="Lia M" last="Haynes">Lia M. Haynes</name><name sortKey="Kiebler, Craig" sort="Kiebler, Craig" uniqKey="Kiebler C" first="Craig" last="Kiebler">Craig Kiebler</name><name sortKey="Miao, Congrong" sort="Miao, Congrong" uniqKey="Miao C" first="Congrong" last="Miao">Congrong Miao</name><name sortKey="Mir, Roger A" sort="Mir, Roger A" uniqKey="Mir R" first="Roger A" last="Mir">Roger A. Mir</name><name sortKey="Pham, Huong" sort="Pham, Huong" uniqKey="Pham H" first="Huong" last="Pham">Huong Pham</name><name sortKey="Pringle, Kimberly" sort="Pringle, Kimberly" uniqKey="Pringle K" first="Kimberly" last="Pringle">Kimberly Pringle</name><name sortKey="Pringle, Kimberly" sort="Pringle, Kimberly" uniqKey="Pringle K" first="Kimberly" last="Pringle">Kimberly Pringle</name><name sortKey="Russell, Elizabeth S" sort="Russell, Elizabeth S" uniqKey="Russell E" first="Elizabeth S" last="Russell">Elizabeth S. Russell</name><name sortKey="Tamin, Azaibi" sort="Tamin, Azaibi" uniqKey="Tamin A" first="Azaibi" last="Tamin">Azaibi Tamin</name><name sortKey="Thornburg, Natalie J" sort="Thornburg, Natalie J" uniqKey="Thornburg N" first="Natalie J" last="Thornburg">Natalie J. Thornburg</name></country><country name="États-Unis"><region name="Maryland"><name sortKey="Kim, Lindsay" sort="Kim, Lindsay" uniqKey="Kim L" first="Lindsay" last="Kim">Lindsay Kim</name></region><name sortKey="Harris, Aaron M" sort="Harris, Aaron M" uniqKey="Harris A" first="Aaron M" last="Harris">Aaron M. Harris</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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